Publications

Mesbahi H, Pho KB, Tench A, Leon Guerrero V, MacNeil LT.  (2020) C. elegans ELT-3 regulates cuticle collagen expression in response to environmental stimuli. Genetics (in review).

Rashid S, Pho KB, Mesbahi H, MacNeil LT. (2020) Nutrient sensing and response drive developmental progression in Caenorhabditis elegans. BioEssays. https://doi.org/10.1002/bies.201900194

Pho KB, MacNeil LT. (2019) Biology is the root of variability: cautionary tales in Caenorhabditis elegans biology. Biochemical Society Transactions 47(3):BST20190001.

Vera-Cruz AG, Amon S, Rashid A, MacNeil LT. (2018). wrt-2 expression oscillates during larval development.  microPublication: biology. https://doi.org/10.17912/4BW7-EP56. 2018.

 

Hu Q, D’Amora DR, MacNeil LT, Walhout AJM, Kubiseski TJ. (2018). The Caenorhabditis elegans oxidative stress response requires the NHR-49 transcription factor. G3 8:3857-3863. 

 

Marko VA, Kilmurry SLN, MacNeil LT, Burrows LL. (2018). Pseudomonas aeruginosa type IV minor pilins and PilY1 regulate virulence by modulating FimS-AlgR activity. PLoS Pathog. 18;14(5):e1007074. 

Yan, A, Culp E, Perry J, Lau JT, MacNeil LT, Surette MG, Wright GD. (2018). Transformation of the anticancer drug doxorubicin in the human microbiome. ACS Infect Dis 4(1):68-76.

 

Hu Q, D’Amora DR, MacNeil LT, Walhout AJM, Kubiseski TJ. (2017). The GATA transcription factor ELT-3 is required for SKN-1/Nrf2 dependent oxidative stress response in C. elegans. Genetics 206(4):1909-1922.

 

Rashid, S, MacNeil LT. (2017). Packing on the pounds in response to bacterial growth conditions. Dev. Cell. 41(4):335-336.

 

Leulier F, MacNeil LT, Lee WJ, Rawls JF, Cani PD, Schwarzer M, Zhao L, Simpson SJ. (2017). Integrative Physiology: At the crossroads of nutrition, microbiota, animal physiology and human health. Cell Metabolism. 25(3):522-534.

 

MacNeil, LT, Pons, C, Arda, HE, Giese, GE, Myers, CL, Walhout, AJM. (2015). Transcription factor activity mapping of a tissue-specific in vivo gene regulatory network . Cell Systems 2:152-162.

 

Conte, D Jr., MacNeil, LT, Walhout, AJM, and Mello, CC. (2015). RNA Interference in Caenorhabditis elegans. Curr. Protoc. Mol. Biol. 109:26.3.1-26.3.30.

 

 Watson, E, MacNeil, LT, Ritter, AD, Yilmaz, LS, Rosebrock, AP, Caudy, AA, Walhout, AJM. (2014). Interspecies systems biology uncovers metabolites affecting C. elegans gene expression and life history traits.  Cell 156:759-70.

 

MacNeil LT, Watson E, Arda HE, Zhu LJ, Walhout AJM. (2013). Diet-induced developmental acceleration independent of TOR and insulin in C. elegans. Cell 153:240-252.

Faculty of 1000 recommended

 

*Watson E, *MacNeil LT, Arda HE, Zhu LJ, Walhout AJM. (2013). Integration of metabolic and gene regulatory networks modulates the C. elegans dietary response.  Cell 153:253-266.

*Equal contribution

 

MacNeil LT, Walhout AJM. (2013). Food, pathogen, signal: the multifaceted nature of a bacterial diet. Worm 2:4, e26454.

 

MacNeil LT, Walhout AJM. (2011). Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression. Genome Res. 21:645-57.

 

Arda HE, Taubert S, MacNeil LT, Conine CC, Tsuda B, Van Gilst M, Sequerra R, Doucette-Stamm L, Yamamoto KR, Walhout AJM. (2010). Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network.  Mol. Sys. Biol.  6:367.

 

Gumienny TL, MacNeil L, Zimmerman CM, Wang H, Chin L, Wrana JL, Padgett, RW. (2010). Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling.  PloS Genetics 6: e1000963.

 

MacNeil LT, Hardy WR, Pawson AJ, Wrana JL, Culotti JG. (2009).  UNC-129 alters the response to UNC-6/Netrin by regulating the decision between UNC-40 dependent and independent UNC-5 signaling. Nature Neuroscience 12:150-5.

 

Kurpios N, MacNeil LT, Shepherd TG, Hassell JA. (2009). PEA3 ets gene functions during morphogenesis and stem cell differentiation in the mouse mammary gland. Dev. Biol. 325:106-21.

 

Gumienny TL, MacNeil LT, Wang H, de Bono M, Wrana, JL, Padgett, RW. (2007). Glypican LON-2 is a conserved negative regulator of BMP-like signaling in Caenorhabditis elegans.  Current Biol. 17, 159-64.

 

 

 

© 2015 MacNeil Lab