Publications

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MacNeil LT, Schertzer JD, Steinberg GR. (2020) Bacteria transmit metformin-associated lifespan extension. Nature Reviews Endocrinology 16(1),9-10.

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Mesbahi H, Pho KB, Tench A, Leon Guerrero V, MacNeil LT.  (2020) C. elegans ELT-3 regulates cuticle collagen expression in response to environmental stimuli. Genetics 215:483-495.

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Rashid S, Pho KB, Mesbahi H, MacNeil LT. (2020) Nutrient sensing and response drive developmental progression in Caenorhabditis elegans. BioEssays. https://doi.org/10.1002/bies.201900194

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Pho KB, MacNeil LT. (2019) Biology is the root of variability: cautionary tales in Caenorhabditis elegans biology. Biochemical Society Transactions 47(3):BST20190001.

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Vera-Cruz AG, Amon S, Rashid A, MacNeil LT. (2018). wrt-2 expression oscillates during larval development.  microPublication: biology. https://doi.org/10.17912/4BW7-EP56.

 

Hu Q, D’Amora DR, MacNeil LT, Walhout AJM, Kubiseski TJ. (2018). The Caenorhabditis elegans oxidative stress response requires the NHR-49 transcription factor. G3 8:3857-3863. 

 

Marko VA, Kilmurry SLN, MacNeil LT, Burrows LL. (2018). Pseudomonas aeruginosa type IV minor pilins and PilY1 regulate virulence by modulating FimS-AlgR activity. PLoS Pathog. 18;14(5):e1007074. 

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Yan, A, Culp E, Perry J, Lau JT, MacNeil LT, Surette MG, Wright GD. (2018). Transformation of the anticancer drug doxorubicin in the human microbiome. ACS Infect Dis 4(1):68-76.

 

Hu Q, D’Amora DR, MacNeil LT, Walhout AJM, Kubiseski TJ. (2017). The GATA transcription factor ELT-3 is required for SKN-1/Nrf2 dependent oxidative stress response in C. elegans. Genetics 206(4):1909-1922.

 

Rashid, S, MacNeil LT. (2017). Packing on the pounds in response to bacterial growth conditions. Dev. Cell. 41(4):335-336.

 

Leulier F, MacNeil LT, Lee WJ, Rawls JF, Cani PD, Schwarzer M, Zhao L, Simpson SJ. (2017). Integrative Physiology: At the crossroads of nutrition, microbiota, animal physiology and human health. Cell Metabolism. 25(3):522-534.

 

MacNeil, LT, Pons, C, Arda, HE, Giese, GE, Myers, CL, Walhout, AJM. (2015). Transcription factor activity mapping of a tissue-specific in vivo gene regulatory network . Cell Systems 2:152-162.

 

Conte, D Jr., MacNeil, LT, Walhout, AJM, and Mello, CC. (2015). RNA Interference in Caenorhabditis elegans. Curr. Protoc. Mol. Biol. 109:26.3.1-26.3.30.

 

Watson, E, MacNeil, LT, Ritter, AD, Yilmaz, LS, Rosebrock, AP, Caudy, AA, Walhout, AJM. (2014). Interspecies systems biology uncovers metabolites affecting C. elegans gene expression and life history traits.  Cell 156:759-70.

 

MacNeil LT, Watson E, Arda HE, Zhu LJ, Walhout AJM. (2013). Diet-induced developmental acceleration independent of TOR and insulin in C. elegans. Cell 153:240-252.

Faculty of 1000 recommended

 

*Watson E, *MacNeil LT, Arda HE, Zhu LJ, Walhout AJM. (2013). Integration of metabolic and gene regulatory networks modulates the C. elegans dietary response.  Cell 153:253-266.

*Equal contribution

 

MacNeil LT, Walhout AJM. (2013). Food, pathogen, signal: the multifaceted nature of a bacterial diet. Worm 2:4, e26454.

 

MacNeil LT, Walhout AJM. (2011). Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression. Genome Res. 21:645-57. ​

 

Arda HE, Taubert S, MacNeil LT, Conine CC, Tsuda B, Van Gilst M, Sequerra R, Doucette-Stamm L, Yamamoto KR, Walhout AJM. (2010). Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network.  Mol. Sys. Biol.  6:367.

 

Gumienny TL, MacNeil L, Zimmerman CM, Wang H, Chin L, Wrana JL, Padgett, RW. (2010). Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling.  PloS Genetics 6: e1000963.

 

MacNeil LT, Hardy WR, Pawson AJ, Wrana JL, Culotti JG. (2009).  UNC-129 alters the response to UNC-6/Netrin by regulating the decision between UNC-40 dependent and independent UNC-5 signaling. Nature Neuroscience 12:150-5.

 

Kurpios N, MacNeil LT, Shepherd TG, Hassell JA. (2009). PEA3 ets gene functions during morphogenesis and stem cell differentiation in the mouse mammary gland. Dev. Biol. 325:106-21.

 

Gumienny TL, MacNeil LT, Wang H, de Bono M, Wrana, JL, Padgett, RW. (2007). Glypican LON-2 is a conserved negative regulator of BMP-like signaling in Caenorhabditis elegans.  Current Biol. 17, 159-64.